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ProductsBack/5-Formylcytosines (5-fC) DNA Matched Antibody Pair
Detection of 5-Formylcytosines (5-fC) in linear denatured DNA (426 bp). Sandwich ELISA using anti-Formylcytosines (5-fC) (clone RM477) as the capture antibody (50ng/well at 1ug/mL), and biotinylated anti-Adenine and Guanine (clone RM476) as the detection antibody (0.2ug/mL), followed by an AP conjugated streptavidin.
Detection of 5-Formylcytosines (5-fC) in linear denatured DNA (426 bp). Sandwich ELISA using anti-Formylcytosines (5-fC) (clone RM477) as the capture antibody (50ng/well at 1ug/mL), and biotinylated anti-Adenine and Guanine (clone RM476) as the detection antibody (0.2ug/mL), followed by an AP conjugated streptavidin.
Detection of 5-Formylcytosines (5-fC) in linear denatured DNA (426 bp). Sandwich ELISA using anti-Formylcytosines (5-fC) (clone RM477) as the capture antibody (50ng/well at 1ug/mL), and biotinylated anti-Adenine and Guanine (clone RM476) as the detection antibody (0.2ug/mL), followed by an AP conjugated streptavidin.

5-Formylcytosines (5-fC) DNA Matched Antibody Pair

Research Use Only
REV-31-1369-MK
RevMAb Biosciences
Product group Antibodies
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Overview

  • Supplier
    RevMAb Biosciences
  • Product Name
    5-Formylcytosines (5-fC) DNA Matched Antibody Pair
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Scientific Description
    5-Formylcytosine (5fC) is a pyrimidine nitrogen base derived from cytosine and a recently discovered modification of DNA. Just as 5-hydroxymethylcytosine (5-hmC) is generated when the Tet family of cytosine oxygenase enzymes converts 5-methylcytosine (5-mC), it has been shown that continued activity of the Tet proteins on hydroxymethylcytosine will generate 5-formylcytosine (5-fC) and 5-carboxylcytosine. It is believed that this conversion process may represent a pathway of DNA demethylation. - Matched Pair Detection Set. This antibody pair detects 5-Formylcytosines (5-fC) in denatured DNA (single strand DNA). It does not react to non-methylated cytosine and other modified cytosine (5-mC, 5-hmC, or 5-caC) in DNA. This product includes capture and detection antibodies for Sandwich ELISA assays.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203

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