7alpha,25-Dihydroxycholesterol [64907-22-8]
HY-113962
CAS Number64907-22-8
Product group Chemicals
Estimated Purity99.88
Molecular Weight418.65
Overview
- SupplierMedChem Express
- Product Name7alpha,25-Dihydroxycholesterol [64907-22-8]
- Delivery Days Customer10
- CAS Number64907-22-8
- CertificationResearch Use Only
- Estimated Purity99.88
- Molecular FormulaC27H46O3
- Molecular Weight418.65
- Scientific Description7alpha, 25-dihydroxycholesterol (7alpha,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7alpha, 25-dihydroxycholesterol is highly potent at activating EBI2 (EC50=140 pM; Kd=450 pM). 7alpha, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells[1][2].
- SMILESC[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)(O)C)([H])[C@@]3([H])[C@]([C@@]4(C(C[C@@H](O)CC4)=C[C@H]3O)C)([H])CC1
- Storage Instruction-20°C
- UNSPSC12352200
MSDS
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