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7alpha,25-Dihydroxycholesterol

ORB1089765
Biorbyt
CAS Number64907-22-8
Product group Chemicals
Molecular Weight418.652349
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Overview

  • Supplier
    Biorbyt
  • Product Name
    7alpha,25-Dihydroxycholesterol [64907-22-8]
  • Delivery Days Customer
    10
  • CAS Number
    64907-22-8
  • Certification
    Research Use Only
  • Molecular Formula
    C27H46O3
  • Molecular Weight
    418.652349
  • Scientific Description
    7alpha, 25-dihydroxycholesterol (7alpha,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7alpha, 25-dihydroxycholesterol is highly potent at activating EBI2 (EC50=140 pM; Kd=450 pM). 7alpha, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells.
  • SMILES
    OC1C=C2C(C)(CCC(O)C2)C2C1C1C(C)(CC2)C(C(C)CCCC(O)(C)C)CC1
  • UNSPSC
    12352200