7alpha,25-Dihydroxycholesterol
ORB1089765
CAS Number64907-22-8
Product group Chemicals
Molecular Weight418.652349
Overview
- SupplierBiorbyt
- Product Name7alpha,25-Dihydroxycholesterol [64907-22-8]
- Delivery Days Customer10
- CAS Number64907-22-8
- CertificationResearch Use Only
- Molecular FormulaC27H46O3
- Molecular Weight418.652349
- Scientific Description7alpha, 25-dihydroxycholesterol (7alpha,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7alpha, 25-dihydroxycholesterol is highly potent at activating EBI2 (EC50=140 pM; Kd=450 pM). 7alpha, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells.
- SMILESOC1C=C2C(C)(CCC(O)C2)C2C1C1C(C)(CC2)C(C(C)CCCC(O)(C)C)CC1
- UNSPSC12352200
![7alpha,25-Dihydroxycholesterol [64907-22-8]](https://www.targetmol.com/group3/M00/35/98/CgoaEWayJXeERsyKAAAAAFWtD9c184.png)