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A-3 (hydrochloride) [78957-85-4]

HY-125957
MedChem Express
CAS Number78957-85-4
Product group Chemicals
Estimated Purity99.75
Molecular Weight321.22
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Overview

  • Supplier
    MedChem Express
  • Product Name
    A-3 (hydrochloride) [78957-85-4]
  • Delivery Days Customer
    9
  • CAS Number
    78957-85-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.75
  • Molecular Formula
    C12H14Cl2N2O2S
  • Molecular Weight
    321.22
  • Scientific Description
    A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It against PKA (Ki=4.3 microM), casein kinase II (Ki=5.1 microM) and myosin light chain kinase (MLCK) (Ki=7.4 microM). A-3 hydrochloride also inhibits PKC and casein kinase I with Ki values of 47 microM and 80 microM, respectively[1].
  • SMILES
    O=S(C1=C2C=CC=C(Cl)C2=CC=C1)(NCCN)=O.[H]Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200