A3 hydrochloride

AbMole BioScience

A3 hydrochloride

9

78957-85-4

Chemical

Research Use Only

C12H13ClN2O2S · HCl

321.22

A-3 Hydrochloride is A potent, cellular permeable, reversible, atP-competitive, non-selective antagonist targeting multiple kinases. A-3 Hydrochloride is an inhibitor of PKA (Ki=4.3 uM), casein kinase II (Ki=5.1 uM), and myosin light chain kinase (MLCK) (Ki=7.4 uM). A-3 hydrochloride also inhibited PKC and casein kinase I activity with Ki of 47 uM and 80 uM, respectively.

Cl.NCCN[S](=O)(=O)C1=C2C=CC=C(Cl)C2=CC=C1

4°C, dry, sealed

12352200