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A-3 hydrochloride [78957-85-4]

A-3 hydrochloride [78957-85-4]

T14069
TargetMol Chemicals
CAS Number78957-85-4
Product group Chemicals
Estimated Purity99.79%
Molecular Weight321.22
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    A-3 hydrochloride [78957-85-4]
  • Delivery Days Customer
    4
  • CAS Number
    78957-85-4
  • Certification
    Research Use Only
  • Chemical Name
    A-3 hydrochloride
  • Estimated Purity
    99.79%
  • Molecular Formula
    C12H14Cl2N2O2S
  • Molecular Weight
    321.22
  • Scientific Description
    A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It inhibits PKC and casein kinase I with Ki values of 47 microM and 80 microM, respectively[1], and also inhibits PKA (Ki=4.3 microM), casein kinase II (Ki=5.1 microM), and myosin light chain kinase (MLCK) (Ki=7.4 microM).
  • Shelf life instruction
    3 years
  • SMILES
    Cl.NCCNS(=O)(=O)c1cccc2c(Cl)cccc12
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200