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A-366 [1527503-11-2]

A-366 [1527503-11-2]

T3624
TargetMol Chemicals
CAS Number1527503-11-2
DownloadMSDS
Product group Chemicals
Estimated Purity98.53%
Molecular Weight329.44
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    A-366 [1527503-11-2]
  • Delivery Days Customer
    9
  • CAS Number
    1527503-11-2
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    A-366
  • Estimated Purity
    98.53%
  • Molecular Formula
    C19H27N3O2
  • Molecular Weight
    329.44
  • Scientific Description
    A-366 is a highly selective peptide-competitive histone methyltransferase G9a inhibitor with IC50s of 3.3 and 38 nM for G9a and GLP, respectively.It is more than 1,000-fold selective for G9a and GLP over the other 21 methyltransferases. It is an inhibitor of the Spindlin1-H3K4me3 interaction with an IC50 of 182.6 nM.It exhibits high affinity for human H3R with a Ki value of 17 nM, and shows subtype selectivity between subgroups of the histaminergic and dopaminergic receptor families.
  • Shelf life instruction
    3 years
  • SMILES
    COc1cc2c(cc1OCCCN1CCCC1)N=C(N)C21CCC1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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