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ABCB11 Polyclonal Antibody

Research Use Only
RD85120A
Reddot Biotech
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetABCB11
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    ABCB11 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ImmunoFluorescence
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID8647
  • Target name
    ABCB11
  • Target description
    ATP binding cassette subfamily B member 11
  • Target synonyms
    ABC member 16, MDR/TAP subfamily; ABC16; ATP-binding cassette sub-family B member 11; ATP-binding cassette, sub-family B (MDR/TAP), member 11; bile salt export pump; BRIC2; BSEP; PFIC2; PFIC-2; PGY4; progressive familial intrahepatic cholestasis 2; sister p-glycoprotein; SPGP
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203