ABCB11 Polyclonal Antibody
RD85120A
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetABCB11
Overview
- SupplierReddot Biotech
- Product NameABCB11 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID8647
- Target nameABCB11
- Target descriptionATP binding cassette subfamily B member 11
- Target synonymsABC member 16, MDR/TAP subfamily; ABC16; ATP-binding cassette sub-family B member 11; ATP-binding cassette, sub-family B (MDR/TAP), member 11; bile salt export pump; BRIC2; BSEP; PFIC2; PFIC-2; PGY4; progressive familial intrahepatic cholestasis 2; sister p-glycoprotein; SPGP
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203