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Western Blot analysis of Human fetal brain tissue using ABI1 Polyclonal Antibody at dilution of 1:300
Western Blot analysis of Human fetal brain tissue using ABI1 Polyclonal Antibody at dilution of 1:300
Western Blot analysis of Human fetal brain tissue using ABI1 Polyclonal Antibody at dilution of 1:300

ABI1 Polyclonal Antibody

Research Use Only
E-AB-15453
Elabscience
Product group Antibodies
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More than 130 suppliers
ISO certified
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Overview

  • Supplier
    Elabscience
  • Product Name
    ABI1 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    ELISA WB IHC
  • Certification
    Research Use Only
  • Concentration
    0.6mg/ml
  • Scientific Description
    This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14
  • UNSPSC
    12352203