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Immunohistochemistry of paraffin-embedded Human brain tissue using ABL1 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human brain tissue using ABL1 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human brain tissue using ABL1 Polyclonal Antibody at dilution 1:40

ABL1 Polyclonal Antibody

Research Use Only
E-AB-10119
Elabscience
Product group Antibodies
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More than 130 suppliers
ISO certified
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Overview

  • Supplier
    Elabscience
  • Product Name
    ABL1 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    ELISA IHC
  • Certification
    Research Use Only
  • Concentration
    0.5mg/ml
  • Scientific Description
    The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1.
  • UNSPSC
    12352203