ABL1/ABL2 (Ab-393/439) Antibody

Cusabio

ABL1/ABL2 (Ab-393/439) Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

ABL1

ABL proto-oncogene 1, non-receptor tyrosine kinase

ABL, BCR-ABL, CHDSKM, JTK7, bcr/abl, c-ABL, c-ABL1, p150, v-abl, tyrosine-protein kinase ABL1, ABL protooncogene 1 nonreceptor tyrosine kinase, Abelson tyrosine-protein kinase 1, BCR-ABL1 p190, BCR/ABL e8a2 fusion, BCR/ABL1 e1a2 fusion protein, BCR/ABL1 fusion, BCR/ABL1 fusion protein e3a1, BCR::ABL1 fusion protein, bcr/c-abl oncogene protein, c-abl oncogene 1, receptor tyrosine kinase, chimeric BCR::ABL1 protein, proto-oncogene c-Abl, proto-oncogene tyrosine-protein kinase ABL1, v-abl Abelson murine leukemia viral oncogene homolog 1

Rabbit

IgG

Tyrosine-protein kinase ABL1

Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks. Wang, J.Y. et al. (2000) Oncogene 19, 5643-5650. Danial, N.N. et al. (2000) Oncogene 19, 2523-2531. Brasher, B.B. et al. (2000) J. Biol. Chem. 275, 35631-35637. Pluk, H. et al. (2002) Cell 108, 247-259.

Human, Mouse

-20°C or -80°C

41116161