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Western blot analysis of extract from MCF-7, 293, HepG2 cells using ABL1/2 (Ab-393/439) Antibody.
Western blot analysis of extract from MCF-7, 293, HepG2 cells using ABL1/2 (Ab-393/439) Antibody.
Western blot analysis of extract from MCF-7, 293, HepG2 cells using ABL1/2 (Ab-393/439) Antibody.

ABL1/ABL2 (Ab-393/439) Antibody

CSB-PA562429
Cusabio
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetABL1
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Overview

  • Supplier
    Cusabio
  • Product Name
    ABL1/ABL2 (Ab-393/439) Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID25
  • Target name
    ABL1
  • Target description
    ABL proto-oncogene 1, non-receptor tyrosine kinase
  • Target synonyms
    Abelson tyrosine-protein kinase 1; ABL; ABL protooncogene 1 nonreceptor tyrosine kinase; bcr/abl; bcr/c-abl oncogene protein; BCR-ABL; c-ABL; c-abl oncogene 1, receptor tyrosine kinase; c-ABL1; CHDSKM; JTK7; p150; proto-oncogene c-Abl; proto-oncogene tyrosine-protein kinase ABL1; truncated ABL protooncogene 1 nonreceptor tyrosine kinase; tyrosine-protein kinase ABL1; v-abl; v-abl Abelson murine leukemia viral oncogene homolog 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP00519
  • Protein Name
    Tyrosine-protein kinase ABL1
  • Scientific Description
    Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks. Wang, J.Y. et al. (2000) Oncogene 19, 5643-5650. Danial, N.N. et al. (2000) Oncogene 19, 2523-2531. Brasher, B.B. et al. (2000) J. Biol. Chem. 275, 35631-35637. Pluk, H. et al. (2002) Cell 108, 247-259.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203