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ABL2 antibody [N1N3]

GTX103584
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetABL2
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Overview

  • Supplier
    GeneTex
  • Product Name
    ABL2 antibody [N1N3]
  • Delivery Days Customer
    9
  • Antibody Specificity
    Knockdown/Knockout validation was supported by references (PMID:27293031)
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.77 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID27
  • Target name
    ABL2
  • Target description
    ABL proto-oncogene 2, non-receptor tyrosine kinase
  • Target synonyms
    Abelson tyrosine-protein kinase 2; abelson-related gene protein; ABLL; ARG; c-abl oncogene 2, non-receptor tyrosine kinase; tyrosine-protein kinase ABL2; tyrosine-protein kinase ARG; v-abl Abelson murine leukemia viral oncogene homolog 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP42684
  • Protein Name
    Tyrosine-protein kinase ABL2
  • Scientific Description
    This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinase. The protein is highly similar to the ABL1 protein, including the tyrosine kinase, SH2 and SH3 domains, and has a role in cytoskeletal rearrangements by its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ETV6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Imatinib and Nilotinib increase glioblastoma cell invasion via Abl-independent stimulation of p130Cas and FAK signalling. Frolov A et al., 2016 Jun 13, Sci Rep
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