Ac-FLTD-CMK [2376255-48-8]
HY-111675
CAS Number2376255-48-8
Product group Chemicals
Estimated Purity99.44%
Molecular Weight569.05
Overview
- SupplierMedChem Express
- Product NameAc-FLTD-CMK [2376255-48-8]
- Delivery Days Customer10
- CAS Number2376255-48-8
- CertificationResearch Use Only
- Estimated Purity99.44%
- Molecular FormulaC26H37ClN4O8
- Molecular Weight569.05
- Scientific DescriptionAc-FLTD-CMK, a gasdermin D (GSDMD)-derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK is effective against caspases-1 (IC50 of 46.7 nM), caspases-4 (IC50 of 1.49 microM), caspases-5 (IC50 of 329 nM), and caspases-11 , but not the apoptotic caspases such as caspase-3.
- SMILESClCC([C@H](CC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CC(C)C)NC([C@@H](NC(C)=O)CC1=CC=CC=C1)=O)=O)=O)=O
- Storage Instruction-20°C,-80°C
- UNSPSC12352200