Ac-FLTD-CMK

MedChem Express

Ac-FLTD-CMK [2376255-48-8]

10

2376255-48-8

Research Use Only

99.53

C26H37ClN4O8

569.05

Ac-FLTD-CMK, a gasdermin D (GSDMD)-derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK is effective against caspases-1 ( IC 50 of 46.7 nM), caspases-4 ( IC 50 of 1.49 microM), caspases-5 ( IC 50 of 329 nM), and caspases-11 , but not the apoptotic caspases such as caspase-3 [1] .

ClCC([C@H](CC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CC(C)C)NC([C@@H](NC(C)=O)CC1=CC=CC=C1)=O)=O)=O)=O

-20°C

12352200