Ac-FLTD-CMK

AbMole BioScience

Ac-FLTD-CMK

9

2376255-48-8

Chemical

Research Use Only

C26H37ClN4O8

569.05

Ac-FLTD-CMK is a gasdermin D (GSDMD)-derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK is effective against caspases-1 (IC50 of 46.7 nM), caspases-4 (IC50 of 1.49 uM), caspases-5 (IC50 of 329 nM), and caspases-11 , but not the apoptotic caspases such as caspase-3.

CC(C)CC(NC(=O)C(CC1=CC=CC=C1)NC(C)=O)C(=O)NC(C(C)O)C(=O)NC(CC(O)=O)C(=O)CCl

-20°C, protect from light, sealed

12352200