Ac-FLTD-CMK [2376255-48-8]

TargetMol Chemicals

Ac-FLTD-CMK [2376255-48-8]

9

2376255-48-8

Chemical

Research Use Only

Ac-FLTD-CMK

0.9517

C26H37ClN4O8

569.05

Ac-FLTD-CMK is an inhibitor derived from abscisicin D (GSDMDD) with specific inhibitory effects on inflammatory caspases. ac-FLTD-CMK showed inhibitory effects on caspases-1, caspases-4 and caspases-11 with IC50s of 46.7 nM, 1.49 microM and 329 nM, respectively. Ac-FLTD-CMK showed potency against caspases-1, caspases-4 and caspases-11, but not against apoptosis-associated caspase-3.

3 years

CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)CCl

-20°C

12352200