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Ac-FLTD-CMK [2376255-48-8]

Ac-FLTD-CMK [2376255-48-8]

T36819
TargetMol Chemicals
CAS Number2376255-48-8
DownloadMSDS
Product group Chemicals
Estimated Purity0.9517
Molecular Weight569.05
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Ac-FLTD-CMK [2376255-48-8]
  • Delivery Days Customer
    9
  • CAS Number
    2376255-48-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Ac-FLTD-CMK
  • Estimated Purity
    0.9517
  • Molecular Formula
    C26H37ClN4O8
  • Molecular Weight
    569.05
  • Scientific Description
    Ac-FLTD-CMK is an inhibitor derived from abscisicin D (GSDMDD) with specific inhibitory effects on inflammatory caspases. ac-FLTD-CMK showed inhibitory effects on caspases-1, caspases-4 and caspases-11 with IC50s of 46.7 nM, 1.49 microM and 329 nM, respectively. Ac-FLTD-CMK showed potency against caspases-1, caspases-4 and caspases-11, but not against apoptosis-associated caspase-3.
  • Shelf life instruction
    3 years
  • SMILES
    CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)CCl
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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