ACAT1 antibody [N1N3]
GTX102637
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Zebra Fish
TargetACAT1
Overview
- SupplierGeneTex
- Product NameACAT1 antibody [N1N3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID38
- Target nameACAT1
- Target descriptionacetyl-CoA acetyltransferase 1
- Target synonymsACAT, MAT, T2, THIL, acetyl-CoA acetyltransferase, mitochondrial, acetoacetyl Coenzyme A thiolase, acetoacetyl-CoA thiolase, acetyl-Coenzyme A acetyltransferase 1, mitochondrial acetoacetyl-CoA thiolase, testicular tissue protein Li 198
- HostRabbit
- IsotypeIgG
- Protein IDP24752
- Protein NameAcetyl-CoA acetyltransferase, mitochondrial
- Scientific DescriptionThis gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone. [provided by RefSeq]
- ReactivityHuman, Mouse, Zebra Fish
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Yano H, Fujiwara Y, Horlad H, et al. Blocking cholesterol efflux mechanism is a potential target for antilymphoma therapy. Cancer Sci. 2022,113(6):2129-2143. doi: 10.1111/cas.15349Read this paper
- Chimalapati S, de Souza Santos M, Lafrance AE, et al. Vibrio deploys type 2 secreted lipase to esterify cholesterol with host fatty acids and mediate cell egress. Elife. 2020,9. doi: 10.7554/eLife.58057Read this paper
- Chen JF, Tsai YT, Lai YH, et al. Proteomic analysis of Antrodia Cinnamomea-induced ER stress in liver cancer cells. J Pharm Biomed Anal. 2020,187:113142. doi: 10.1016/j.jpba.2020.113142Read this paper
- Lo YW, Lin ST, Chang SJ, et al. Mitochondrial proteomics with siRNA knockdown to reveal ACAT1 and MDH2 in the development of doxorubicin-resistant uterine cancer. J Cell Mol Med. 2015,19(4):744-59. doi: 10.1111/jcmm.12388Read this paper
- Kato K, Yazawa T, Taki K, et al. The inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration. Mol Biol Cell. 2012,23(13):2593-604. doi: 10.1091/mbc.E11-11-0958Read this paper





