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ProductsBack/Acidic Cytokeratin antibody [AE1]

Acidic Cytokeratin antibody [AE1]

GTX80320
GeneTex
ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityBovine, Chicken, Human, Monkey, Mouse, Porcine, Rabbit, Rat
TargetKRT1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Acidic Cytokeratin antibody [AE1]
  • Delivery Days Customer
    9
  • Antibody Specificity
    Recognizes low molecular weight cytokeratins CK 10, CK14, CK15, CK16 and CK19 of the acidic family.
  • Applications
    ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    AE1
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3848
  • Target name
    KRT1
  • Target description
    keratin 1
  • Target synonyms
    67 kDa cytokeratin; CK1; CK-1; cytokeratin 1; EHK; EHK1; epidermolytic hyperkeratosis 1; EPPK; hair alpha protein; K1; keratin 1, type II; keratin, type II cytoskeletal 1; KRT1A; NEPPK; type-II keratin Kb1
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
  • Reactivity
    Bovine, Chicken, Human, Monkey, Mouse, Porcine, Rabbit, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Characterization of immortalized human epidermolysis bullosa simplex (KRT5) cell lines: trimethylamine N-oxide protects the keratin cytoskeleton against disruptive stress condition. Chamcheu JC et al., 2009 Mar, J Dermatol Sci
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