Acidic Cytokeratin antibody [AE1]
GTX80320
Overview
- SupplierGeneTex
- Product NameAcidic Cytokeratin antibody [AE1]
- Delivery Days Customer9
- Antibody SpecificityRecognizes low molecular weight cytokeratins CK 10, CK14, CK15, CK16 and CK19 of the acidic family.
- Clone IDAE1
- Concentration1 mg/ml
- FormulationLiquid
- Gene ID3848
- Target nameKRT1
- Target descriptionkeratin 1
- Target synonyms67 kDa cytokeratin; CK1; CK-1; cytokeratin 1; EHK; EHK1; epidermolytic hyperkeratosis 1; EPPK; hair alpha protein; K1; keratin 1, type II; keratin, type II cytoskeletal 1; KRT1A; NEPPK; type-II keratin Kb1
- Scientific DescriptionThe protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Characterization of immortalized human epidermolysis bullosa simplex (KRT5) cell lines: trimethylamine N-oxide protects the keratin cytoskeleton against disruptive stress condition. Chamcheu JC et al., 2009 Mar, J Dermatol SciRead more