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Actinonin

ORB1089764
Biorbyt
CAS Number13434-13-4
Product group Chemicals
Molecular Weight385.4983
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Overview

  • Supplier
    Biorbyt
  • Product Name
    Actinonin [13434-13-4]
  • Delivery Days Customer
    10
  • CAS Number
    13434-13-4
  • Certification
    Research Use Only
  • Molecular Formula
    C19H35N3O5
  • Molecular Weight
    385.4983
  • Scientific Description
    Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM. Actinonin also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin alpha with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities.
  • SMILES
    CCCCCC(CC(=O)NO)C(=O)NC(C(C)C)C(=O)N1C(CO)CCC1
  • UNSPSC
    12352200