AF488 Anti-Human/Mouse/Rat CD47 Antibody
RD20314F
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCD47
Overview
- SupplierReddot Biotech
- Product NameAF488 Anti-Human/Mouse/Rat CD47 Antibody
- Delivery Days Customer5
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMIAP410
- Concentration0.5 mg/ml
- ConjugateAlexaFluor 488
- Gene ID961
- Target nameCD47
- Target descriptionCD47 molecule
- Target synonymsantigen identified by monoclonal antibody 1D8; antigenic surface determinant protein OA3; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); CD47 glycoprotein; IAP; integrin associated protein; integrin-associated signal transducer; leukocyte surface antigen CD47; MER6; OA3; Rh-related antigen
- HostMouse
- IsotypeIgG1
- Scientific DescriptionCD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPOe+/-, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C
- UNSPSC12352203