AF647 Anti-Human CD39 Antibody

Reddot Biotech

AF647 Anti-Human CD39 Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

A1

AlexaFluor 647

ENTPD1

ectonucleoside triphosphate diphosphohydrolase 1

ATP-DPH, ATPDase, CD39, NTPDase-1, SPG64, ectonucleoside triphosphate diphosphohydrolase 1, ATP diphosphohydrolase, CD39 antigen, NTPDase1, ecto-ATP diphosphohydrolase 1, ecto-ATPDase 1, ecto-ATPase 1, ecto-apyrase, lymphoid cell activation antigen, nucleoside triphosphate diphosphohydrolase 1

Mouse

IgG1

Human CD39 is an integral membrane protein with two transmembrane domains. It exists as a homotetramer. Expression of CD39 is found on activated lymphocytes, a subset of T cells and B cells, and dendritic cells with weak staining on monocytes and granulocytes. CD39 and CD73 have been found on regulatory T cells, specifically the effector/memory like T cells. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. CD39 is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 has intrinsic ecto-ATPase activity. Expression of CD39 is induced on T cells and increased on B cells as a late activation antigen. Product Details

Human

2°C to 8°C

12352203