AFG3L2 Antibody, FITC conjugated

Cusabio

AFG3L2 Antibody, FITC conjugated

20

Research Use Only

Polyclonal

FITC

AFG3L2

AFG3 like matrix AAA peptidase subunit 2

OPA12, SCA28, SPAX5, mitochondrial inner membrane m-AAA protease component AFG3L2, AFG3 ATPase family gene 3-like 2, AFG3 ATPase family member 3-like 2, AFG3 like AAA ATPase 2, AFG3-like protein 2, ATPase family gene 3, yeast, paraplegin-like protein

Rabbit

IgG

Mitochondrial inner membrane m-AAA protease component AFG3L2

ATP-dependent protease which is essential for axonal and neuron development. In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, limiting the availability of SMDT1/EMRE for MCU assembly and promoting efficient assembly of gatekeeper subunits with MCU (PubMed:27642048). Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form (By similarity).

Human

-20°C or -80°C

41116161