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AFG3L2 antibody [N1N2], N-term

GTX102036
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetAFG3L2
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Overview

  • Supplier
    GeneTex
  • Product Name
    AFG3L2 antibody [N1N2], N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID10939
  • Target name
    AFG3L2
  • Target description
    AFG3 like matrix AAA peptidase subunit 2
  • Target synonyms
    OPA12, SCA28, SPAX5, mitochondrial inner membrane m-AAA protease component AFG3L2, AFG3 ATPase family gene 3-like 2, AFG3 ATPase family member 3-like 2, AFG3 like AAA ATPase 2, AFG3-like protein 2, ATPase family gene 3, yeast, paraplegin-like protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9Y4W6
  • Protein Name
    Mitochondrial inner membrane m-AAA protease component AFG3L2
  • Scientific Description
    This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Akabane S, Watanabe K, Kosako H, et al. TIM23 facilitates PINK1 activation by safeguarding against OMA1-mediated degradation in damaged mitochondria. Cell Rep. 2023,42(5):112454. doi: 10.1016/j.celrep.2023.112454
    Read this paper
  • Correia SP, Chan AB, Vaughan M, et al. The circadian E3 ligase complex SCF(FBXL3+CRY) targets TLK2. Sci Rep. 2019,9(1):198. doi: 10.1038/s41598-018-36618-3
    Read this paper