![WB analysis of various samples using GTX03179 Aggrecan antibody [GT1267]. Dilution : 1:1000 Loading : 25microg per lane WB analysis of various samples using GTX03179 Aggrecan antibody [GT1267]. Dilution : 1:1000 Loading : 25microg per lane](https://www.genetex.com/upload/website/prouct_img/normal/GTX03179/GTX03179_14_WB_w_23053123_891.webp)
WB analysis of various samples using GTX03179 Aggrecan antibody [GT1267]. Dilution : 1:1000 Loading : 25microg per lane
Aggrecan antibody [GT1267]
GTX03179
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetACAN
Overview
- SupplierGeneTex
- Product NameAggrecan antibody [GT1267]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGT1267
- Concentration1.5 mg/ml
- ConjugateUnconjugated
- Gene ID176
- Target nameACAN
- Target descriptionaggrecan
- Target synonymsAGC1, AGCAN, CSPG1, CSPGCP, MSK16, SEDK, SSOAOD, aggrecan core protein, cartilage-specific proteoglycan core protein, chondroitin sulfate proteoglycan core protein 1, large aggregating proteoglycan
- HostRabbit
- IsotypeIgG
- Protein IDP16112
- Protein NameAggrecan core protein
- Scientific DescriptionThis gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq, Jul 2008]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Meng N, Mao L, Jiang Q, et al. PLXNC1 interference alleviates the inflammatory injury, apoptosis and extracellular matrix degradation of IL-1β-exposed chondrocytes via suppressing GRP78 expression. J Orthop Surg Res. 2023,18(1):784. doi: 10.1186/s13018-023-04207-4Read this paper
- Chang YH, Ding DC, Wu KC. Human Umbilical Mesenchymal Stromal Cells Mixed with Hyaluronan Transplantation Decreased Cartilage Destruction in a Rabbit Osteoarthritis Model. Stem Cells Int. 2021,2021:2989054. doi: 10.1155/2021/2989054Read this paper
![IHC-P analysis of rat bone marrow tissue section using GTX03179 Aggrecan antibody [GT1267]. Dilution : 1:100 IHC-P analysis of rat bone marrow tissue section using GTX03179 Aggrecan antibody [GT1267]. Dilution : 1:100](https://www.genetex.com/upload/website/prouct_img/normal/GTX03179/GTX03179_20210615_IHC-P_11_w_23053123_551.webp)
![IHC-P analysis of mouse bone marrow tissue section using GTX03179 Aggrecan antibody [GT1267]. Dilution : 1:100 IHC-P analysis of mouse bone marrow tissue section using GTX03179 Aggrecan antibody [GT1267]. Dilution : 1:100](https://www.genetex.com/upload/website/prouct_img/normal/GTX03179/GTX03179_20210615_IHC-P_12_w_23053123_145.webp)
![Various whole cell extracts (30 microg) were separated by 5% SDS-PAGE, and the membrane was blotted with Aggrecan antibody [GT1267] (GTX03179) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program. Various whole cell extracts (30 microg) were separated by 5% SDS-PAGE, and the membrane was blotted with Aggrecan antibody [GT1267] (GTX03179) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.](https://www.genetex.com/upload/website/prouct_img/normal/GTX03179/GTX03179_4000000678_20210709_WB_w_23053123_939.webp)




![WB analysis of human aggrecan recombinant protein using GTX31216 Aggrecan antibody [7D4].](https://www.genetex.com/upload/website/prouct_img/normal/GTX31216/GTX31216_69_WB_w_23060722_313.webp)

