Bio-Connect
IHC-P analysis of formalin fixed human lung cancer tissue section using GTX54920 Aggrecan antibody. Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)
IHC-P analysis of formalin fixed human lung cancer tissue section using GTX54920 Aggrecan antibody. Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)
IHC-P analysis of formalin fixed human lung cancer tissue section using GTX54920 Aggrecan antibody. Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)

Aggrecan antibody

GTX54920
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Porcine, Rat
TargetACAN
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    Aggrecan antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500 - 1:1000. IHC-P: 1:100 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID176
  • Target name
    ACAN
  • Target description
    aggrecan
  • Target synonyms
    AGC1; AGCAN; aggrecan core protein; cartilage-specific proteoglycan core protein; chondroitin sulfate proteoglycan core protein 1; CSPG1; CSPGCP; large aggregating proteoglycan; MSK16; SEDK; SSOAOD
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP16112
  • Protein Name
    Aggrecan core protein
  • Scientific Description
    This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse, Porcine, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Denosumab alleviates intervertebral disc degeneration adjacent to lumbar fusion by inhibiting endplate osteochondral remodeling and vertebral osteoporosis in ovariectomized rats. Sun Q et al., 2021 May 28, Arthritis Res Ther
    Read more
  • A novel 3D histotypic cartilage construct engineered by supercritical carbon dioxide decellularized porcine nasal cartilage graft and chondrocytes exhibited chondrogenic capability in vitro. Lee SS et al., 2021, Int J Med Sci
    Read more
  • Kartogenin Enhances Chondrogenic Differentiation of MSCs in 3D Tri-Copolymer Scaffolds and the Self-Designed Bioreactor System. Chen CY et al., 2021 Jan 16, Biomolecules
    Read more
  • Raloxifene inhibits the overexpression of TGF-beta1 in cartilage and regulates the metabolism of subchondral bone in rats with osteoporotic osteoarthritis. Ping SH et al., 2021 Jun 1, Bosn J Basic Med Sci
    Read more
  • 3D composite engineered using supercritical CO2 decellularized porcine cartilage scaffold, chondrocytes, and PRP: Role in articular cartilage regeneration. Chen YT et al., 2021 Feb, J Tissue Eng Regen Med
    Read more
  • Parathyroid hormone (1-34) ameliorates cartilage degeneration and subchondral bone deterioration in collagenase-induced osteoarthritis model in mice. Shao LT et al., 2020 Oct, Bone Joint Res
    Read more
  • Impaired autophagy triggered by HDAC9 in mesenchymal stem cells accelerates bone mass loss. Zhang L et al., 2020 Jul 3, Stem Cell Res Ther
    Read more
  • Optimization of Protocol for Isolation of Chondrocytes from Human Articular Cartilage. Muhammad SA et al., 2021 Dec, Cartilage
    Read more