IHC-P analysis of formalin fixed human lung cancer tissue section using GTX54920 Aggrecan antibody. Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)
IHC-P analysis of formalin fixed human lung cancer tissue section using GTX54920 Aggrecan antibody. Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)
Aggrecan antibody
GTX54920
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Porcine, Rat
TargetACAN
Overview
- SupplierGeneTex
- Product NameAggrecan antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:1000. IHC-P: 1:100 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID176
- Target nameACAN
- Target descriptionaggrecan
- Target synonymsAGC1; AGCAN; aggrecan core protein; cartilage-specific proteoglycan core protein; chondroitin sulfate proteoglycan core protein 1; CSPG1; CSPGCP; large aggregating proteoglycan; MSK16; SEDK; SSOAOD
- HostRabbit
- IsotypeIgG
- Protein IDP16112
- Protein NameAggrecan core protein
- Scientific DescriptionThis gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Porcine, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Skeletal diseases caused by mutations in PTH1R show aberrant differentiation of skeletal progenitors due to dysregulation of DEPTOR.Read more
- Protective effects of equol on the cartilage and subchondral bone in ovariectomized rats with osteoarthritis.Read more
- Denosumab alleviates intervertebral disc degeneration adjacent to lumbar fusion by inhibiting endplate osteochondral remodeling and vertebral osteoporosis in ovariectomized rats. Sun Q et al., 2021 May 28, Arthritis Res TherRead more
- A novel 3D histotypic cartilage construct engineered by supercritical carbon dioxide decellularized porcine nasal cartilage graft and chondrocytes exhibited chondrogenic capability in vitro. Lee SS et al., 2021, Int J Med SciRead more
- Kartogenin Enhances Chondrogenic Differentiation of MSCs in 3D Tri-Copolymer Scaffolds and the Self-Designed Bioreactor System. Chen CY et al., 2021 Jan 16, BiomoleculesRead more
- Raloxifene inhibits the overexpression of TGF-beta1 in cartilage and regulates the metabolism of subchondral bone in rats with osteoporotic osteoarthritis. Ping SH et al., 2021 Jun 1, Bosn J Basic Med SciRead more
- 3D composite engineered using supercritical CO2 decellularized porcine cartilage scaffold, chondrocytes, and PRP: Role in articular cartilage regeneration. Chen YT et al., 2021 Feb, J Tissue Eng Regen MedRead more
- Parathyroid hormone (1-34) ameliorates cartilage degeneration and subchondral bone deterioration in collagenase-induced osteoarthritis model in mice. Shao LT et al., 2020 Oct, Bone Joint ResRead more
- Impaired autophagy triggered by HDAC9 in mesenchymal stem cells accelerates bone mass loss. Zhang L et al., 2020 Jul 3, Stem Cell Res TherRead more
- Optimization of Protocol for Isolation of Chondrocytes from Human Articular Cartilage. Muhammad SA et al., 2021 Dec, CartilageRead more