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WB analysis of mouse liver lysate using GTX89149 AGTR1 antibody, Internal. Dilution : 0.3microg/ml Loading : 35microg protein in RIPA buffer
WB analysis of mouse liver lysate using GTX89149 AGTR1 antibody, Internal. Dilution : 0.3microg/ml Loading : 35microg protein in RIPA buffer
WB analysis of mouse liver lysate using GTX89149 AGTR1 antibody, Internal. Dilution : 0.3microg/ml Loading : 35microg protein in RIPA buffer

AGTR1 antibody, Internal

GTX89149
GeneTex
ApplicationsWestern Blot
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
TargetAGTR1
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Overview

  • Supplier
    GeneTex
  • Product Name
    AGTR1 antibody, Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 0.3-1microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.50 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID185
  • Target name
    AGTR1
  • Target description
    angiotensin II receptor type 1
  • Target synonyms
    AG2S; AGTR1B; AT1; AT1AR; AT1B; AT1BR; AT1R; AT2R1; HAT1R; type-1 angiotensin II receptor; type-1B angiotensin II receptor
  • Host
    Goat
  • Isotype
    IgG
  • Protein IDP30556
  • Protein Name
    Type-1 angiotensin II receptor
  • Scientific Description
    Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Elevated blood pressure in high-fat diet-exposed low birthweight rat offspring is most likely caused by elevated glucocorticoid levels due to abnormal pituitary negative feedback. Nemoto T et al., 2020, PLoS One
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  • Increased AT2R expression is induced by AT1R autoantibody via two axes, Klf-5/IRF-1 and circErbB4/miR-29a-5p, to promote VSMC migration. Sun Y et al., 2020 Jun 8, Cell Death Dis
    Read more