AKAP12 Polyclonal Antibody

Reddot Biotech

AKAP12 Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.4 mg/ml

Unconjugated

AKAP12

A-kinase anchoring protein 12

A kinase (PRKA) anchor protein 12; AKAP 250; AKAP250; A-kinase anchor protein 12; A-kinase anchor protein, 250kDa; kinase scaffold protein gravin; myasthenia gravis autoantigen gravin; Src-Suppressed C Kinase Substrate; SSeCKS

Rabbit

IgG

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

-20°C

12352203