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Western Blot analysis of PC3 cells using AKT1 Monoclonal Antibody at dilution of 1:1000.
Western Blot analysis of PC3 cells using AKT1 Monoclonal Antibody at dilution of 1:1000.
Western Blot analysis of PC3 cells using AKT1 Monoclonal Antibody at dilution of 1:1000.

AKT1 Monoclonal Antibody

Research Use Only
E-AB-22211
Elabscience
Product group Antibodies
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More than 130 suppliers
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Overview

  • Supplier
    Elabscience
  • Product Name
    AKT1 Monoclonal Antibody
  • Delivery Days Customer
    12
  • Certification
    Research Use Only
  • Scientific Description
    The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery.
  • UNSPSC
    12352203