ALDH2 antibody
GTX101429
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetALDH2
Overview
- SupplierGeneTex
- Product NameALDH2 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. ELISA: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.23 mg/ml
- ConjugateUnconjugated
- Gene ID217
- Target nameALDH2
- Target descriptionaldehyde dehydrogenase 2 family member
- Target synonymsALDH-E2, ALDHI, ALDM, aldehyde dehydrogenase, mitochondrial, ALDH class 2, acetaldehyde dehydrogenase 2, aldehyde dehydrogenase 2 family (mitochondrial), epididymis secretory sperm binding protein, liver mitochondrial ALDH, nucleus-encoded mitochondrial aldehyde dehydrogenase 2
- HostRabbit
- IsotypeIgG
- Protein IDP05091
- Protein NameAldehyde dehydrogenase, mitochondrial
- Scientific DescriptionThis protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Lin YH, Yang YF, Liao JB, et al. Analysis of Aldehyde Dehydrogenase 2 as a Prognostic Marker Associated with Immune Cell infiltration and Chemotherapy Efficacy in Head and Neck Squamous Cell Carcinoma. J Cancer. 2023,14(10):1689-1706. doi: 10.7150/jca.85098Read this paper
- Masato A, Plotegher N, Terrin F, et al. DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections in Parkinson's disease. NPJ Parkinsons Dis. 2023,9(1):42. doi: 10.1038/s41531-023-00485-1Read this paper
- Chen SM, Hee SW, Chou SY, et al. Activation of Aldehyde Dehydrogenase 2 Ameliorates Glucolipotoxicity of Pancreatic Beta Cells. Biomolecules. 2021,11(10). doi: 10.3390/biom11101474Read this paper
- Kitakaze T, Yuan S, Inoue M, et al. 6-(Methylsulfinyl)hexyl isothiocyanate protects acetaldehyde-caused cytotoxicity through the induction of aldehyde dehydrogenase in hepatocytes. Arch Biochem Biophys. 2020,686:108329. doi: 10.1016/j.abb.2020.108329Read this paper
- Gueugneau M, Coudy-Gandilhon C, Gourbeyre O, et al. Proteomics of muscle chronological ageing in post-menopausal women. BMC Genomics. 2014,15:1165. doi: 10.1186/1471-2164-15-1165Read this paper
- Liu S, Yeh TH, Singh VP, et al. β-catenin is essential for ethanol metabolism and protection against alcohol-mediated liver steatosis in mice. Hepatology. 2012,55(3):931-40. doi: 10.1002/hep.24766Read this paper



![ICC/IF analysis of COS7 cells transiently transfected with ALDH2 plasmid using GTX84890 ALDH2 antibody [4H2].](https://www.genetex.com/upload/website/prouct_img/normal/GTX84890/GTX84890_1277_ICCIF_w_23061420_726.webp)

