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ALDH2 antibody

GTX101429
GeneTex
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetALDH2
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Overview

  • Supplier
    GeneTex
  • Product Name
    ALDH2 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. ELISA: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.23 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID217
  • Target name
    ALDH2
  • Target description
    aldehyde dehydrogenase 2 family member
  • Target synonyms
    acetaldehyde dehydrogenase 2; aldehyde dehydrogenase 2 family (mitochondrial); aldehyde dehydrogenase, mitochondrial; ALDH class 2; ALDH-E2; ALDHI; ALDM; epididymis secretory sperm binding protein; liver mitochondrial ALDH; nucleus-encoded mitochondrial aldehyde dehydrogenase 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP05091
  • Protein Name
    Aldehyde dehydrogenase, mitochondrial
  • Scientific Description
    This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Analysis of Aldehyde Dehydrogenase 2 as a Prognostic Marker Associated with Immune Cell infiltration and Chemotherapy Efficacy in Head and Neck Squamous Cell Carcinoma.
    Read more
  • DOPAL initiates alphaSynuclein-dependent impaired proteostasis and degeneration of neuronal projections in Parkinsons disease. Masato A et al., 2023 Mar 25, NPJ Parkinsons Dis
    Read more
  • Activation of Aldehyde Dehydrogenase 2 Ameliorates Glucolipotoxicity of Pancreatic Beta Cells. Chen SM et al., 2021 Oct 6, Biomolecules
    Read more
  • 6-(Methylsulfinyl)hexyl isothiocyanate protects acetaldehyde-caused cytotoxicity through the induction of aldehyde dehydrogenase in hepatocytes. Kitakaze T et al., 2020 Jun 15, Arch Biochem Biophys
    Read more
  • Proteomics of muscle chronological ageing in post-menopausal women. Gueugneau M et al., 2014 Dec 23, BMC Genomics
    Read more
  • beta-catenin is essential for ethanol metabolism and protection against alcohol-mediated liver steatosis in mice. Liu S et al., 2012 Mar, Hepatology
    Read more

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