
WB analysis of HeLa and A549 cells treated with etoposide 25uM (24h) lysate using GTX86886 alpha Fodrin (cleaved Asp1185) antibody. The lane on the right is blocked with the synthesized peptide.
alpha Fodrin (cleaved Asp1185) antibody
GTX86886
Overview
- SupplierGeneTex
- Product Namealpha Fodrin (cleaved Asp1185) antibody
- Delivery Days Customer9
- Antibody Specificityalpha Fodrin (cleaved Asp1185) antibody detects endogenous levels of fragment of activated alpha Fodrin / SPTA2 resulting from cleavage adjacent to Asp1185.
- Application Supplier NoteWB: 1:500~1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID6709
- Target nameSPTAN1
- Target descriptionspectrin alpha, non-erythrocytic 1
- Target synonymsalpha-fodrin; alpha-II spectrin; DEE5; EIEE5; epididymis secretory sperm binding protein; fodrin alpha chain; NEAS; spectrin alpha chain, non-erythrocytic 1; spectrin, non-erythroid alpha chain; spectrin, non-erythroid alpha subunit; SPTA2
- HostRabbit
- IsotypeIgG
- Protein IDQ13813
- Protein NameSpectrin alpha chain, non-erythrocytic 1
- Scientific DescriptionSpectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203