
WB analysis of HeLa, HepG2, and Jurkat cell lysates using GTX87192 alpha Sarcoglycan antibody. The lane on the right is blocked with the synthesized peptide.
alpha Sarcoglycan antibody
GTX87192
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetSGCA
Overview
- SupplierGeneTex
- Product Namealpha Sarcoglycan antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500~1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID6442
- Target nameSGCA
- Target descriptionsarcoglycan alpha
- Target synonyms50DAG, ADL, DAG2, DMDA2, LGMD2D, LGMDR3, SCARMD1, adhalin, alpha-sarcoglycan, 50 kDa dystrophin-associated glycoprotein, 50kD DAG, alpha-SG, dystroglycan-2, limb girdle muscular dystrophy 2D, sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
- HostRabbit
- IsotypeIgG
- Protein IDQ16586
- Protein NameAlpha-sarcoglycan
- Scientific DescriptionThis gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Perez-Ortiz AC, Peralta-Ildefonso MJ, Lira-Romero E, et al. Lack of Delta-Sarcoglycan (Sgcd) Results in Retinal Degeneration. Int J Mol Sci. 2019,20(21). doi: 10.3390/ijms20215480Read this paper
- Estrada-Mena FJ, Rodriguez A, Mendoza-Lorenzo P, et al. Effects of (-)-epicatechin on frontal cortex DAPC and dysbindin of the mdx mice. Neurosci Lett. 2017,658:142-149. doi: 10.1016/j.neulet.2017.08.056Read this paper




![IHC-Fr analysis of transverse section of skeletal muscle fibers using GTX01939 alpha Sarcoglycan antibody [Ad1/20A6]. Note the demonstration of localized Alpha Sarcoglycan to the sarcolemma of the muscle fibers.](https://www.genetex.com/upload/website/prouct_img/normal/GTX01939/GTX01939_20200811_IHC-Fr_1_w_23053121_827.webp)


