alpha Smooth Muscle Actin antibody [1A4] (ready-to-use)
GTX73419
ApplicationsFlow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetACTA2
Overview
- SupplierGeneTex
- Product Namealpha Smooth Muscle Actin antibody [1A4] (ready-to-use)
- Delivery Days Customer9
- Application Supplier Note*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1A4
- ConjugateUnconjugated
- Gene ID59
- Target nameACTA2
- Target descriptionactin alpha 2, smooth muscle
- Target synonymsACTSA, SMDYS, actin, aortic smooth muscle, actin, alpha 2, smooth muscle, aorta, alpha-cardiac actin, cell growth-inhibiting gene 46 protein
- HostMouse
- IsotypeIgG2a
- Protein IDP62736
- Protein NameActin, aortic smooth muscle
- Scientific DescriptionThis gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome. [provided by RefSeq, Sep 2017]
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
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- Varga DP, Szabó Í, Varga VÉ, et al. The antagonism of prostaglandin FP receptors inhibits the evolution of spreading depolarization in an experimental model of global forebrain ischemia. Neurobiol Dis. 2020,137:104780. doi: 10.1016/j.nbd.2020.104780Read this paper
- Li DJ, Fu H, Tong J, et al. Cholinergic anti-inflammatory pathway inhibits neointimal hyperplasia by suppressing inflammation and oxidative stress. Redox Biol. 2018,15:22-33. doi: 10.1016/j.redox.2017.11.013Read this paper
- Aslani F, Schuppe HC, Guazzone VA, et al. Targeting high mobility group box protein 1 ameliorates testicular inflammation in experimental autoimmune orchitis. Hum Reprod. 2015,30(2):417-31. doi: 10.1093/humrep/deu320Read this paper
- Backhouse S, Phillips JR. Effect of induced myopia on scleral myofibroblasts and in vivo ocular biomechanical compliance in the guinea pig. Invest Ophthalmol Vis Sci. 2010,51(12):6162-71. doi: 10.1167/iovs.10-5387Read this paper
- Akishima-Fukasawa Y, Ino Y, Nakanishi Y, et al. Significance of PGP9.5 expression in cancer-associated fibroblasts for prognosis of colorectal carcinoma. Am J Clin Pathol. 2010,134(1):71-9. doi: 10.1309/AJCPRJP39MIDSGBHRead this paper






![FACS analysis of L929 cells using GTX17501 alpha Smooth Muscle Actin antibody [9H15] (PE).](https://www.genetex.com/upload/website/prouct_img/normal/GTX17501/GTX17501_20191203_FACS_0_w_23060620_472.webp)