alpha Smooth Muscle Actin antibody [1A4] (FITC)
GTX72531
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetACTA2
Overview
- SupplierGeneTex
- Product Namealpha Smooth Muscle Actin antibody [1A4] (FITC)
- Delivery Days Customer9
- Application Supplier NoteFor IF: Use at 10-20 microg/ml for 2 hours at room temperature. For IF: paraffin-embedded or frozen sections, as well as on cell smears can be used. Optimal dilutions/concentrations should be determined by the end user.
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1A4
- ConjugateFITC
- Gene ID59
- Target nameACTA2
- Target descriptionactin alpha 2, smooth muscle
- Target synonymsACTSA, SMDYS, actin, aortic smooth muscle, actin, alpha 2, smooth muscle, aorta, alpha-cardiac actin, cell growth-inhibiting gene 46 protein
- HostMouse
- IsotypeIgG2a
- Protein IDP62736
- Protein NameActin, aortic smooth muscle
- Scientific DescriptionThis gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome. [provided by RefSeq, Sep 2017]
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Bisaccia P, Magarotto F, D'Agostino S, et al. Extracellular Vesicles From Mesenchymal Umbilical Cord Cells Exert Protection Against Oxidative Stress and Fibrosis in a Rat Model of Bronchopulmonary Dysplasia. Stem Cells Transl Med. 2024,13(1):43-59. doi: 10.1093/stcltm/szad070Read this paper
- Zhou Z, Van der Jeught K, Li Y, et al. A T Cell-Engaging Tumor Organoid Platform for Pancreatic Cancer Immunotherapy. Adv Sci (Weinh). 2023,10(23):e2300548. doi: 10.1002/advs.202300548Read this paper
- Kecskés S, Menyhárt Á, Bari F, et al. Nimodipine augments cerebrovascular reactivity in aging but runs the risk of local perfusion reduction in acute cerebral ischemia. Front Aging Neurosci. 2023,15:1175281. doi: 10.3389/fnagi.2023.1175281Read this paper
- Medley SC, Rathnakar BH, Georgescu C, et al. Fibroblast-specific Stat1 deletion enhances the myofibroblast phenotype during tissue repair. Wound Repair Regen. 2020,28(4):448-459. doi: 10.1111/wrr.12807Read this paper
- Varga DP, Szabó Í, Varga VÉ, et al. The antagonism of prostaglandin FP receptors inhibits the evolution of spreading depolarization in an experimental model of global forebrain ischemia. Neurobiol Dis. 2020,137:104780. doi: 10.1016/j.nbd.2020.104780Read this paper
- Gorchs L, Hellevik T, Bruun JA, et al. Cancer-associated fibroblasts from lung tumors maintain their immunosuppressive abilities after high-dose irradiation. Front Oncol. 2015,5:87. doi: 10.3389/fonc.2015.00087Read this paper
- Wan W, Liu Q, Lionakis MS, et al. Atypical chemokine receptor 1 deficiency reduces atherogenesis in ApoE-knockout mice. Cardiovasc Res. 2015,106(3):478-87. doi: 10.1093/cvr/cvv124Read this paper
- Aslani F, Schuppe HC, Guazzone VA, et al. Targeting high mobility group box protein 1 ameliorates testicular inflammation in experimental autoimmune orchitis. Hum Reprod. 2015,30(2):417-31. doi: 10.1093/humrep/deu320Read this paper
- Backhouse S, Phillips JR. Effect of induced myopia on scleral myofibroblasts and in vivo ocular biomechanical compliance in the guinea pig. Invest Ophthalmol Vis Sci. 2010,51(12):6162-71. doi: 10.1167/iovs.10-5387Read this paper
- Akishima-Fukasawa Y, Ino Y, Nakanishi Y, et al. Significance of PGP9.5 expression in cancer-associated fibroblasts for prognosis of colorectal carcinoma. Am J Clin Pathol. 2010,134(1):71-9. doi: 10.1309/AJCPRJP39MIDSGBHRead this paper






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