alpha Smooth Muscle Actin antibody [1A4] (FITC)

GeneTex

alpha Smooth Muscle Actin antibody [1A4] (FITC)

9

This antibody reacts with the alpha-smooth muscle isoform of actin. It does not react with actin from fibroblasts (beta- and gamma-cytoplasmic), striated muscle (alpha-sarcomeric) and myocardium (alpha-myocardial).

For IF: Use at 10-20 microg/ml for 2 hours at room temperature. For IF: paraffin-embedded or frozen sections, as well as on cell smears can be used. Optimal dilutions/concentrations should be determined by the end user.

Flow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

1A4

FITC

Liquid

ACTA2

actin alpha 2, smooth muscle

actin, alpha 2, smooth muscle, aorta; actin, aortic smooth muscle; ACTSA; alpha-cardiac actin; cell growth-inhibiting gene 46 protein

Mouse

IgG2a

Actin, aortic smooth muscle

This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome. [provided by RefSeq, Sep 2017]

Guinea Pig, Human, Mouse, Primate, Rabbit, Rat

2°C to 8°C

12352203