
WB analysis of various samples using GTX57554 alpha Synuclein antibody. Samples : Recombinant Human protein of synuclein family (alpha-, beta- and gamma-) and alpha-synuclein domains (1-60, 1-95, 61-140 and 96-140) Dilution : 1:1000
alpha Synuclein antibody [5C2]
GTX57554
Overview
- SupplierGeneTex
- Product Namealpha Synuclein antibody [5C2]
- Delivery Days Customer9
- Antibody SpecificityBased on internal testing result, this antibody does not cross react with human beta- and gamma-synuclein.This antibody specifically recognizes the NAC domain (61-95aa) of alpha-synuclein.
- Application Supplier NoteWB: 1:500-1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID5C2
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID6622
- Target nameSNCA
- Target descriptionsynuclein alpha
- Target synonymsalpha-synuclein; I+/--synuclein; NACP; non A-beta component of AD amyloid; PARK1; PARK4; PD1; synuclein alpha-140; synuclein, alpha (non A4 component of amyloid precursor); truncated alpha synuclein
- HostMouse
- IsotypeIgG1
- Protein IDP37840
- Protein NameAlpha-synuclein
- Scientific DescriptionAlpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimers disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203