Alsterpaullone [237430-03-4]

AdipoGen Life Sciences

Alsterpaullone

10

237430-03-4

Research Use Only

>98%

Warning

C16H11N3O3

293.3

Chemical. CAS: 237430-03-4. Formula: C16H11N3O3. MW: 293.3. Potent CDK1/cyclin B (IC50 = 35 nM) inhibitor. Anti-tumor compound Potent inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50 = 200 nM), CDK5/p25 (IC50 = 40 nM), CDK5/p35 (IC50 = 40 nM). GSK-3beta (glycogen synthase kinase-3beta) inhibitor. Apoptosis inhibitor. Apoptosis inducer. Angiogenesis inhibitor. - Potent CDK1/cyclin B (IC50 = 35 nM) inhibitor [1]. Anti-tumor compound [1] Potent inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50 = 200 nM), CDK5/p25 (IC50 = 40 nM), CDK5/p35 (IC50 = 40 nM) [2, 4]. GSK-3beta (glycogen synthase kinase-3beta) inhibitor [2, 3]. Apoptosis inhibitor [6, 7]. Apoptosis inducer [5]. Angiogenesis inhibitor [8].

[O-][N+](=O)C1=CC2=C(NC3=C2CC(=O)NC2=C3C=CC=C2)C=C1

2°C to 8°C

12352200