AMACR antibody [13H4]
GTX01579
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetAMACR
Overview
- SupplierGeneTex
- Product NameAMACR antibody [13H4]
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1:150. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID13h4
- ConjugateUnconjugated
- Gene ID23600
- Target nameAMACR
- Target descriptionalpha-methylacyl-CoA racemase
- Target synonymsAMACRD, CBAS4, P504S, RACE, RM, alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase
- HostRabbit
- IsotypeIgG
- Protein IDQ9UHK6
- Protein NameAlpha-methylacyl-CoA racemase
- Scientific DescriptionThis gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Hasan IA, Gaidan HA, Al-Kaabi MM. Diagnostic Value of Cytokeratin 34 beta E12 (Ck34βE12) and α-Methylacyl-CoA racemase (AMACR) Immunohistochemical Expression in Prostatic Lesions. Iran J Pathol. 2020,15(3):232-238. doi: 10.30699/ijp.2020.113544.2229Read this paper
- Popov BV, Sutula GI, Petrov NS, et al. Preparation and characterization of the antibody recognizing AMACR inside its catalytic center. Int J Oncol. 2018,52(2):547-559. doi: 10.3892/ijo.2017.4220Read this paper
- Fadare O, Zhao C, Khabele D, et al. Comparative analysis of Napsin A, alpha-methylacyl-coenzyme A racemase (AMACR, P504S), and hepatocyte nuclear factor 1 beta as diagnostic markers of ovarian clear cell carcinoma: an immunohistochemical study of 279 ovarian tumours. Pathology. 2015,47(2):105-11. doi: 10.1097/PAT.0000000000000223Read this paper
Datasheet
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