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AMG 232

M10374
AbMole BioScience
CAS Number1352066-68-2
Product group Chemicals
Molecular Weight568.55
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    AMG 232
  • Delivery Days Customer
    9
  • CAS Number
    1352066-68-2
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C28H35Cl2NO5S
  • Molecular Weight
    568.55
  • Scientific Description
    AMG 232 is an extremely potent MDM2 inhibitor (SPR KD = 0.045 nM, SJSA-1 EdU IC50 = 9.1 nM), with remarkable pharmacokinetic properties and in vivo antitumor activity in the SJSA-1 osteosarcoma xenograft model (ED50 = 9.1 mg/kg). *The compound is unstable in solutions, freshly prepared is recommended
  • UNSPSC
    12352200