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Navtemadlin [1352066-68-2]

Navtemadlin [1352066-68-2]

TQ0127
TargetMol Chemicals
CAS Number1352066-68-2
Product group Chemicals
Estimated Purity98.86%
Molecular Weight568.55
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Navtemadlin [1352066-68-2]
  • Delivery Days Customer
    4
  • CAS Number
    1352066-68-2
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Navtemadlin
  • Estimated Purity
    98.86%
  • Molecular Formula
    C28H35Cl2NO5S
  • Molecular Weight
    568.55
  • Scientific Description
    Navtemadlin (AMG232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction (IC50: 0.6 nM). It binds to MDM2 with a Kd of 0.045 nM.
  • Shelf life instruction
    3 years
  • SMILES
    CC(C)[C@@H](CS(=O)(=O)C(C)C)N1[C@@H]([C@H](C[C@](C)(CC(O)=O)C1=O)c1cccc(Cl)c1)c1ccc(Cl)cc1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200