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Amphiregulin antibody

GTX100986
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetAREG
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Overview

  • Supplier
    GeneTex
  • Product Name
    Amphiregulin antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.17 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID374
  • Target name
    AREG
  • Target description
    amphiregulin
  • Target synonyms
    amphiregulin; amphiregulin B; AR; AREGB; colorectum cell-derived growth factor; CRDGF; schwannoma-derived growth factor; SDGF
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP15514
  • Protein Name
    Amphiregulin
  • Scientific Description
    The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Aberrant expression of the UPF1 RNA surveillance gene disturbs keratinocyte homeostasis by stabilizing AREG. Yaojia Cheng YX et al., 2020 Apr, Int J Mol Med
    Read more
  • Co-expression and prognostic significance of putative CSC markers CD44, CD133, wild-type EGFR and EGFRvIII in metastatic colorectal cancer. Khelwatty SA et al., 2019 Mar 1, Oncotarget
    Read more
  • The impact of co-expression of wild-type EGFR and its ligands determined by immunohistochemistry for response to treatment with cetuximab in patients with metastatic colorectal cancer. Khelwatty S et al., 2017 Jan 31, Oncotarget
    Read more