
Binding of human Angiopoietin-2 to Tie-2 (human):Fc is inhibited by the antibody anti-Angiopoietin-2 (human), mAb (rec.) (blocking) (Angy-1-4) (preservative free). Methods: Tie-2 (human):Fc was coated on an ELISA plate at 1microg/ml. anti-Angiopoietin-2 (human), mAb (rec.) (blocking), (Angy-1-4) (preservative free) or an unrelated mAb (recombinant) (Control) were added (starting at 40microg/ml with a twofold serial dilution) together with 200ng/microl of Angiopoietin-2 (human). After incubation for 1h at RT, the binding was detected using an anti-FLAG antibody (HRP).
Angiopoietin 2 antibody [Angy-1-4] (Azide free)
GTX33914-00
ApplicationsELISA, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetANGPT2
Overview
- SupplierGeneTex
- Product NameAngiopoietin 2 antibody [Angy-1-4] (Azide free)
- Delivery Days Customer9
- Antibody SpecificityRecognizes human angiopoietin-2. Does not recognize mouse angiopoietin-2 and human angiopoietin-1.
- Application Supplier NoteNeutralizing/Inhibition: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsELISA, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDAngy-1-4
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID285
- Target nameANGPT2
- Target descriptionangiopoietin 2
- Target synonymsAGPT2; ANG2; angiopoietin-2; angiopoietin-2a; angiopoietin-2B; LMPHM10; Tie2-ligand
- HostHuman
- IsotypeIgG2
- Protein IDO15123
- Protein NameAngiopoietin-2
- Scientific DescriptionThe protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203