Western Blot Positive WB detected in: Rat brain tissue, Rat kidney tissue, Mouse brain tissue All lanes: ANGPT2 antibody at 3.2microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 57, 51 kDa Observed band size: 57, 51 kDa
ANGPT2 Antibody
CSB-PA05749A0RB
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetANGPT2
Overview
- SupplierCusabio
- Product NameANGPT2 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID285
- Target nameANGPT2
- Target descriptionangiopoietin 2
- Target synonymsAGPT2; ANG2; angiopoietin-2; angiopoietin-2a; angiopoietin-2B; LMPHM10; Tie2-ligand
- HostRabbit
- IsotypeIgG
- Protein IDO15123
- Protein NameAngiopoietin-2
- Scientific DescriptionBinds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203