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Angiopoietin 2 antibody

GTX100928
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
TargetANGPT2
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Overview

  • Supplier
    GeneTex
  • Product Name
    Angiopoietin 2 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.41 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID285
  • Target name
    ANGPT2
  • Target description
    angiopoietin 2
  • Target synonyms
    AGPT2; ANG2; angiopoietin-2; angiopoietin-2a; angiopoietin-2B; LMPHM10; Tie2-ligand
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO15123
  • Protein Name
    Angiopoietin-2
  • Scientific Description
    The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Etanercept as a TNF-alpha inhibitor depresses experimental retinal neovascularization. Yao Y et al., 2021 Mar, Graefes Arch Clin Exp Ophthalmol
    Read more
  • Targeting the ERbeta/Angiopoietin-2/Tie-2 signaling-mediated angiogenesis with the FDA-approved anti-estrogen Faslodex to increase the Sunitinib sensitivity in RCC. Gu J et al., 2020 May 14, Cell Death Dis
    Read more
  • Hyperglycemia activates the renin-angiotensin system and induces epithelial-mesenchymal transition in streptozotocin-induced diabetic kidneys. Chen CM et al., 2018 Jul-Sep, J Renin Angiotensin Aldosterone Syst
    Read more
  • The Fibrin Cleavage Product Bbeta15-42 Channels Endothelial and Tubular Regeneration in the Post-acute Course During Murine Renal Ischemia Reperfusion Injury. Fischer D et al., 2018, Front Pharmacol
    Read more