The data was published in the journal Front Pharmacol in 2018.
The data was published in the journal Front Pharmacol in 2018.
Angiopoietin 2 antibody
GTX100928
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetANGPT2
Overview
- SupplierGeneTex
- Product NameAngiopoietin 2 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.41 mg/ml
- ConjugateUnconjugated
- Gene ID285
- Target nameANGPT2
- Target descriptionangiopoietin 2
- Target synonymsAGPT2, ANG2, LMPHM10, angiopoietin-2, Tie2-ligand, angiopoietin-2B, angiopoietin-2a
- HostRabbit
- IsotypeIgG
- Protein IDO15123
- Protein NameAngiopoietin-2
- Scientific DescriptionThe protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Yao Y, Cai Y, Sui A, et al. Etanercept as a TNF-alpha inhibitor depresses experimental retinal neovascularization. Graefes Arch Clin Exp Ophthalmol. 2021,259(3):661-671. doi: 10.1007/s00417-020-04956-6Read this paper
- Gu J, Zhang Y, Han Z, et al. Targeting the ERβ/Angiopoietin-2/Tie-2 signaling-mediated angiogenesis with the FDA-approved anti-estrogen Faslodex to increase the Sunitinib sensitivity in RCC. Cell Death Dis. 2020,11(5):367. doi: 10.1038/s41419-020-2486-0Read this paper
- Chen CM, Juan SH, Chou HC. Hyperglycemia activates the renin-angiotensin system and induces epithelial-mesenchymal transition in streptozotocin-induced diabetic kidneys. J Renin Angiotensin Aldosterone Syst. 2018,19(3):1470320318803009. doi: 10.1177/1470320318803009Read this paper
- Fischer D, Seifen C, Baer P, et al. The Fibrin Cleavage Product Bβ(15-42) Channels Endothelial and Tubular Regeneration in the Post-acute Course During Murine Renal Ischemia Reperfusion Injury. Front Pharmacol. 2018,9:369. doi: 10.3389/fphar.2018.00369Read this paper
Datasheet
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