Anti-4-1BB [LOB12.3]

Absolute Antibody

Anti-4-1BB [LOB12.3]

9

This antibody binds to mouse 4-1BB (CD137).

This antibody can be used to detect mouse 4-1BB (CD137). In its original rat IgG1 format, this antibody had agonistic effect and prolonged survival of mice bearing CT26 or A31 tumors. In the original publication another clone LOB12 disclosed which has a rat IgG2a isotype. This has led to some confusion in the literature with regards to the original isotype of LOB12 and LOB12.3. We offer this antibody in both formats as well as murine versions so that researchers may choose the isotype most appropriate for their assays.

Flow Cytometry, Other Application

Research Use Only

Monoclonal

LOB12.3

Tnfrsf9

tumor necrosis factor receptor superfamily, member 9

4-1BB; 4-1BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; ILA; Ly6; Ly63; secreted CD137 antigen; T-cell antigen 4-1BB; tumor necrosis factor receptor superfamily member 9

Human

IgG1

Tumor necrosis factor receptor superfamily member 9

This chimeric human antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Mouse

-20°C,2°C to 8°C

12352203