Bio-Connect

Anti-AGER

Y058663
Applied Biological Materials
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
100 ul
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Applied Biological Materials
  • Product Name
    Anti-AGER
  • Delivery Days Customer
    9
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Host
    Rabbit
  • Scientific Description
    Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203

Related products

Product group Antibodies
RayBiotech
ApplicationsWestern Blot
TargetAGER
  • SizePrice
Product group Antibodies
Biosynth
RAGE antibody20R-RG001
  • SizePrice
Product group Antibodies
Assay Genie
TargetAGER
  • SizePrice
Western Blot analysis of 3T3 cells using RAGE Polyclonal Antibody
Product group Antibodies
Cusabio
AGER AntibodyCSB-PA007810
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
ReactivityHuman
TargetAGER
  • SizePrice
Product group Antibodies
LifeSpan BioSciences
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
TargetAGER
  • SizePrice
Product group Antibodies
Biomatik
ApplicationsImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
TargetAGER
  • SizePrice
Immunohistochemistry analysis in human lung and prostate tissues using AMAb91634 antibody. Corresponding AGER RNA-seq data are presented for the same tissues.
Product group Antibodies
Atlas Antibodies
ApplicationsImmunoHistoChemistry
ReactivityHuman, Rat
TargetAGER
  • SizePrice
Figure 1. Western blot analysis of RAGE/AGER using anti-RAGE/AGER antibody (A03438-1). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 ug of sample under reducing conditions. Lane 1: rat lung tissue lysates, Lane 2: mouse lung tissue lysates. After electrophoresis, proteins were transferred to a nitrocellulose membrane at 150 mA for 50-90 minutes. Blocked the membrane with 5% non-fat milk/TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-RAGE/AGER antigen affinity purified polyclonal antibody (Catalog # A03438-1) at 0.5 microg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:5000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for RAGE/AGER at approximately 45-58 kDa. The expected band size for RAGE/AGER is at 43 kDa.
Product group Antibodies
Boster Bio
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
TargetAGER
  • SizePrice
WB analysis of mouse lung tissue lysate (35ug/lane) using GTX16592 RAGE antibody.
Product group Antibodies
GeneTex
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetAGER
  • SizePrice
Anti-RAGE Antibody
Product group Antibodies
Antibodies.com
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
  • SizePrice