![anti-ANO1 [TMEM16A] (human), Rabbit Monoclonal (RM440) anti-ANO1 [TMEM16A] (human), Rabbit Monoclonal (RM440)](https://adipogen.com/pub/media/catalog/product/r/e/rev-31-1331-00-rm440_fig1_ihc1_dog1.png)
anti-ANO1 [TMEM16A] (human), Rabbit Monoclonal (RM440)
![Research Use Only](static/images/certificates/ruo.jpg)
REV-31-1331-00
Overview
- SupplierRevMAb Biosciences
- Product Nameanti-ANO1 [TMEM16A] (human), Rabbit Monoclonal (RM440)
- Delivery Days Customer5
- Antibody SpecificityThis antibody reacts to human ANO1.
- ApplicationsImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDRM440
- Gene ID55107
- Target nameANO1
- Target descriptionanoctamin 1
- Target synonymsanoctamin 1, calcium activated chloride channel; anoctamin-1; Ca2+-activated Cl- channel; calcium activated chloride channel; discovered on gastrointestinal stromal tumors protein 1; DOG1; oral cancer overexpressed 2; ORAOV2; TAOS2; TMEM16A; transmembrane protein 16A (eight membrane-spanning domains); tumor-amplified and overexpressed sequence 2
- HostRabbit
- IsotypeIgG
- Scientific DescriptionANO1 is a calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. It is required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. ANO1 acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development. Its overexpression was reported in esophageal squamous cell carcinoma and breast cancer progression. - Recombinant Antibody. This antibody reacts to human ANO1. Apllication: IHC. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. ANO1 is a calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. It is required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. ANO1 acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development. Its overexpression was reported in esophageal squamous cell carcinoma and breast cancer progression.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203