anti-Apolipoprotein E antibody [WUE-4]
ARG23067
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetAPOE
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-Apolipoprotein E antibody [WUE-4]
- Delivery Days Customer23
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDWUE-4
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID348
- Target nameAPOE
- Target descriptionapolipoprotein E
- Target synonymsAD2; APO-E; ApoE4; apolipoprotein E; apolipoprotein E3; LDLCQ5; LPG
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203