Mouse Caspase-1 (p10) is detected by immunoblotting using anti-Caspase-1 (p10) (mouse), mAb (Casper-2) (Prod. No AG-20B-0044). Method: Caspase-1 was analyzed by Western blot in supernatants of differentiated bone marrow-derived dendritic cells (BMD
anti-Caspase-1 (p10) (mouse), mAb (Casper-2)
AG-20B-0044
Overview
- SupplierAdipoGen Life Sciences
- Product Nameanti-Caspase-1 (p10) (mouse), mAb (Casper-2)
- Delivery Days Customer10
- Antibody SpecificityRecognizes endogenous full-length and activated (p10 fragment) mouse caspase-1.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDCasper-2
- Concentration1 mg/ml
- Estimated Purity>95%
- FormulationLiquid
- Gene ID12362
- Target nameCasp1
- Target descriptioncaspase 1
- Target synonymsCasp; CASP-1; caspase-1; IC; ICE; Il1; IL-1 beta-converting enzyme; IL-1B converting enzyme; Il1bc; IL-1BC; interleukin-1 beta convertase; interleukin-1 beta-converting enzyme; p45
- HostMouse
- IsotypeIgG2a
- Protein IDP29452
- Protein NameCaspase-1
- Scientific DescriptionCaspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals. - Monoclonal Antibody. Recognizes endogenous full-length and activated (p10 fragment) mouse caspase-1. Isotype: Mouse IgG2a. Clone: Casper-2. Applications: WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.
- ReactivityMouse
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203