Anti-CD11a [NKIL16]

Absolute Antibody

Anti-CD11a [NKIL16]

7

This antibody is specific for CD11a. CD11a is a receptor for ICAM1, ICAM2, ICAM3, ICAM4, F11R, and the secreted form of ubiquitin-like protein ISG15. CD11a is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cyto

To show that the enhanced adhesiveness of CD4+ T cells is induced by CD3 cross-linking, an adhesion assay was performed on human PMBCs using the mouse version of this antibody (Mazerolles et al, 1991; pmid:1826886). An adhesion assay was performed on human T and B cells in the presence of the mouse version of this antibody to study the kinetics of T-cell adhesion (Mazerolles et al, 1991; pmid:1679053).

Functional Assay

functional assay

Research Use Only

Monoclonal

NKIL16

ITGAL

integrin subunit alpha L

antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; CD11 antigen-like family member A; CD11A; integrin alpha-L; integrin gene promoter; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; LFA-1; LFA-1 alpha; LFA1A; LFA-1A; lymphocyte function-associated antigen 1, alpha polypeptide

Human

IgG1

Integrin alpha-L

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format for improved compatibility with existing reagents assays and techniques.

Human

Human

The mouse version of this antibody was raised by immunizing a BALB/c mosue with human cytotoxic T-lymphocytes.

-20°C,2°C to 8°C

12352203