Bio-Connect

anti-CD28 (human), Rabbit Monoclonal (RM404)

Research Use Only
REV-31-1290-00
RevMAb Biosciences
ApplicationsImmunoHistoChemistry, Western Blot
Product group Antibodies
ReactivityHuman
TargetCD28
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    RevMAb Biosciences
  • Product Name
    anti-CD28 (human), Rabbit Monoclonal (RM404)
  • Delivery Days Customer
    5
  • Applications
    ImmunoHistoChemistry, Western Blot
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    RM404
  • Gene ID940
  • Target name
    CD28
  • Target description
    CD28 molecule
  • Target synonyms
    T-cell-specific surface glycoprotein CD28; Tp44
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    CD28 is a homodimeric T cell specific surface glycoprotein. CD28 is a cell adhesion molecule of the immunoglobulin superfamily which is constitutively expressed on most peripheral blood T lymphocytes. Moreover, CD28 is the critical T cell costimulatory receptor that provides the cell the important second activation signal by binding CD80 and CD86 which are expressed by antigen presenting cells. In addition to its co-stimulation role, CD28 functions by preventing T cells from entering an anergic-hyporesponsive state or from undergoing premature apoptotic cell death. In murine peripheral lymphoid organs and in the blood, all CD4+ and CD8+ T cells express CD28. Diseases associated with CD28 dysfunction include mycosis fungiodes and Sezarys Disease. - Recombinant Antibody. This antibody reacts to human to CD28. Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. CD28 is a homodimeric T cell specific surface glycoprotein. CD28 is a cell adhesion molecule of the immunoglobulin superfamily which is constitutively expressed on most peripheral blood T lymphocytes. Moreover, CD28 is the critical T cell costimulatory receptor that provides the cell the important second activation signal by binding CD80 and CD86 which are expressed by antigen presenting cells. In addition to its co-stimulation role, CD28 functions by preventing T cells from entering an anergic-hyporesponsive state or from undergoing premature apoptotic cell death. In murine peripheral lymphoid organs and in the blood, all CD4+ and CD8+ T cells express CD28. Diseases associated with CD28 dysfunction include mycosis fungiodes and Sezarys Disease.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203