Anti-CD325 APC
1A-849
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman, Mouse
Overview
- SupplierEXBIO
- Product NameAnti-CD325 APC
- Delivery Days Customer7
- Application Supplier NoteFlow cytometry: The reagent is designed for analysis of human blood cells using 10 microl reagent / 100 microl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- Clone ID8C11
- ConjugateAPC (Allophycocyanin)
- IsotypeIgG1
- Scientific DescriptionCD325 (N-cadherin) is a type I transmembrane protein, which forms a complex with catenins, that is linked to the actin cytoskeleton. This complex is important in synapses and for functional plasticity of neurons, and is also essential for embryonic development. Decreased CD325 cleavage caused by mutations in presenilin 1 is associated with Alzheimers disease. Besides nervous system, CD325 is expressed on the surface of malignant T cells, and increases their adhesion to epithelia, as well as their ability to invade and metastasize to inflammatory sites.
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203






![Wild-type (WT) and N-Cadherin knockout (KO) 293T cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with N-Cadherin antibody [N2C1], Internal (GTX112733) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX112733/GTX112733_40394_20180810_WB_KO_watermark_w_23060500_602.webp)

