Bio-Connect

Anti-CD325 APC

1A-849
EXBIO
ApplicationsFlow Cytometry
Product group Antibodies
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Overview

  • Supplier
    EXBIO
  • Product Name
    Anti-CD325 APC
  • Delivery Days Customer
    7
  • Application Supplier Note
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 microl reagent / 100 microl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clone ID
    8C11
  • Conjugate
    APC (Allophycocyanin)
  • Isotype
    IgG1
  • Scientific Description
    CD325 (N-cadherin) is a type I transmembrane protein, which forms a complex with catenins, that is linked to the actin cytoskeleton. This complex is important in synapses and for functional plasticity of neurons, and is also essential for embryonic development. Decreased CD325 cleavage caused by mutations in presenilin 1 is associated with Alzheimers disease. Besides nervous system, CD325 is expressed on the surface of malignant T cells, and increases their adhesion to epithelia, as well as their ability to invade and metastasize to inflammatory sites.
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203