Anti-CD39 [I-391]

Absolute Antibody

Anti-CD39 [I-391]

7

The binding characterization of this antibody for CD39 expressed on Ramos cells was done using flow cytometry (WO2018065552). The binding of this antibody to various recombinant human CD39 isoforms was detected using ELISA. This antibody bound only vascular CD39, without any binding to CD39-L1, CD39-L2, CD39-L3 or CD39-L4. This antibody did not induce or increase CD39 down regulation. It was reported that this antibody is very potent at blocking CD39 enzymatic activity and is capable of neutralizing ATPase activity (US20190153113).

Flow Cytometry, ELISA, Neutralisation/Blocking

FC; ELISA; neutralize

Research Use Only

Monoclonal

I-391

ENTPD1

ectonucleoside triphosphate diphosphohydrolase 1

ATP-DPH, ATPDase, CD39, NTPDase-1, SPG64, ectonucleoside triphosphate diphosphohydrolase 1, ATP diphosphohydrolase, CD39 antigen, NTPDase1, ecto-ATP diphosphohydrolase 1, ecto-ATPDase 1, ecto-ATPase 1, ecto-apyrase, lymphoid cell activation antigen, nucleoside triphosphate diphosphohydrolase 1

Mouse

IgG2b

Ectonucleoside triphosphate diphosphohydrolase 1

Human, Monkey

Human, cynomolgus monkey

-20°C,2°C to 8°C

41116161